Description

6-Chloro-2-Fluoro-3-Iodopyridine, 95% is a high-purity halogenated pyridine derivative serving as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials who require reliable access to high-quality, structurally defined intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Precursor: Serves as a starting material for creating functionalized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Aromatic Substitution: The fluorine and chlorine atoms are amenable to selective displacement, allowing for sequential functionalization.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Iodopyridine, 95%
CAS No.	1187732-65-5
Molecular Formula	C5H2ClFIN
Molecular Weight	273.43 g/mol
Synonyms	2-Fluoro-3-iodo-6-chloropyridine; 3-Iodo-6-chloro-2-fluoropyridine; 6-Chloro-2-fluoro-3-iodopyridine; 2-Fluoro-6-chloro-3-iodopyridine; Pyridine, 6-chloro-2-fluoro-3-iodo-; 1187732-65-5; 6-Chloro-2-fluoro-3-iodo-pyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Iodopyridine, 95% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.