Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-5-Chloro-2-Cyclopropyl- is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and cyclopropyl-substituted structure enables precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its halogenated pyrrolopyridine core.
• Material Science: Serves as a precursor for organic electronic materials, including ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-5-Chloro-2-Cyclopropyl-
CAS No.	1187449-10-0
Molecular Formula	C10H8BrClN2
Molecular Weight	271.54 g/mol
Synonyms	4-Bromo-5-chloro-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine; 2-Cyclopropyl-4-bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-5-chloro-2-cyclopropyl-7-azaindole; 2-Cyclopropyl-4-bromo-5-chloro-7-azaindole; 7-Azaindole, 4-bromo-5-chloro-2-cyclopropyl-; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-5-chloro-2-cyclopropyl-; 1187449-10-0; 4-Bromo-5-chloro-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-5-Chloro-2-Cyclopropyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed specifications are provided to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.