Description

4-Bromo-5-Chloro-3-Iodopyridin-2-Amine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides multiple reactive sites for selective functionalization and cross-coupling reactions. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Synthesis: Employed in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex heterocyclic systems.
• Life Science Research: Utilized as a biochemical tool and probe in academic and industrial research laboratories.

Basic Information

Product Name	4-Bromo-5-Chloro-3-Iodopyridin-2-Amine
CAS No.	1187449-04-2
Molecular Formula	C5H3BrClIN2
Molecular Weight	348.35 g/mol
Synonyms	2-Amino-4-bromo-5-chloro-3-iodopyridine; 4-Bromo-5-chloro-3-iodopyridin-2-ylamine; 4-Bromo-5-chloro-3-iodo-2-pyridinamine; 2-Pyridinamine, 4-bromo-5-chloro-3-iodo-; 1187449-04-2; 4-Br-5-Cl-3-I-2-AP; BCI Pyridine Amine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-5-Chloro-3-Iodopyridin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.