Description

1-(6-Bromopyridin-2-Yl)-3-Methyl-5-Trifluoromethylpyrazole is a high-value brominated pyrazole-pyridine hybrid compound, serving as a critical building block in modern synthetic chemistry. Its core value lies in its unique molecular architecture, which combines a halogenated pyridine ring with a trifluoromethyl-substituted pyrazole, enabling precise structural modifications in target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly for applications requiring enhanced metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in constructing advanced active ingredients for crop protection products, leveraging the bioactivity of the pyrazole and pyridine motifs.
• Material Science Research: Serves as a precursor for functionalized ligands in catalytic systems or for creating novel organic frameworks.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Scale-Up: Provides a versatile starting point for contract research organizations (CROs) and CDMOs performing custom synthesis projects.

Basic Information

Product Name	1-(6-Bromopyridin-2-Yl)-3-Methyl-5-Trifluoromethylpyrazole
CAS No.	1187386-44-2
Molecular Formula	C10H7BrF3N3
Molecular Weight	306.08 g/mol
Synonyms	1-(6-Bromo-2-pyridinyl)-3-methyl-5-(trifluoromethyl)-1H-pyrazole; 3-Methyl-5-trifluoromethyl-1-(6-bromopyridin-2-yl)pyrazole; 1-(6-Bromopyridin-2-yl)-3-methyl-5-(trifluoromethyl)-1H-pyrazole; 1-(6-Bromo-2-pyridyl)-3-methyl-5-trifluoromethylpyrazole; 2-(3-Methyl-5-trifluoromethylpyrazol-1-yl)-6-bromopyridine; 6-Bromo-2-(3-methyl-5-trifluoromethyl-1H-pyrazol-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our production of 1-(6-Bromopyridin-2-Yl)-3-Methyl-5-Trifluoromethylpyrazole adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (e.g., REACH) ensures a reliable supply for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.