Description

Hexahydro-Pyrrolo[1,2-A]Pyrazin-6-One Hydrochloride is a high-purity organic salt with significant utility in advanced pharmaceutical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and oncology research pipelines.
• Building Block for API Synthesis: Used to construct the pyrrolopyrazine core structure found in various investigational new drugs.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the exploration of new chemical entities in academic and industrial R&D labs.
• Process Development & Scale-up: Supports the optimization and commercial-scale manufacturing of target compounds under current Good Manufacturing Practices (cGMP).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Hexahydro-Pyrrolo[1,2-A]Pyrazin-6-One Hydrochloride
CAS No.	1187385-53-0
Molecular Formula	C7H12N2O·HCl
Molecular Weight	176.64 g/mol
Synonyms	1,2,3,3a,4,6-Hexahydropyrrolo[1,2-a]pyrazin-6-one hydrochloride; Hexahydro-1H-pyrrolo[1,2-a]pyrazin-6(2H)-one hydrochloride; Pyrrolo[1,2-a]pyrazin-6-one, hexahydro-, hydrochloride; 1187385-53-0; CAS 1187385-53-0
EINECS	Contact for details

Quality Control

Our Hexahydro-Pyrrolo[1,2-A]Pyrazin-6-One Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.