Description

1-Boc-4-(4-Methoxybenzyl)-4-Carboxypiperidine is a high-purity, protected piperidine derivative used as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Peptidomimetic Chemistry: Serves as a constrained amino acid surrogate for designing and synthesizing peptide analogs with improved metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Library Synthesis for Drug Discovery: An essential building block for creating diverse compound libraries via parallel and combinatorial chemistry.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Investigated as a monomer or additive for creating polymers with specific functional properties.

Basic Information

Product Name	1-Boc-4-(4-Methoxybenzyl)-4-Carboxypiperidine
CAS No.	1187172-32-2
Molecular Formula	C19H27NO5
Molecular Weight	349.42 g/mol
Synonyms	1-Boc-4-(4-Methoxybenzyl)piperidine-4-carboxylic acid; 4-[(4-Methoxyphenyl)methyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid; tert-Butyl 4-(4-methoxybenzyl)-4-carboxypiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(4-methoxybenzyl)piperidine-4-carboxylic acid; 4-(4-Methoxybenzyl)-1-Boc-piperidine-4-carboxylic acid; N-Boc-4-(4-methoxybenzyl)isonipecotic acid; BOC-4-(4-Methoxybenzyl)-4-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(4-Methoxybenzyl)-4-Carboxypiperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.