Description

2-Chloro-5-(4-Iodobenzoyl)Pyridine is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs) and functional materials, offering a unique halogenated pyridine core for selective cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a starting material for creating functionalized ligands used in catalysis and organic electronic materials.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthetic chemistry.

Basic Information

Product Name	2-Chloro-5-(4-Iodobenzoyl)Pyridine
CAS No.	1187170-32-6
Molecular Formula	C12H7ClINO
Molecular Weight	343.55 g/mol
Synonyms	5-(4-Iodobenzoyl)-2-chloropyridine; (4-Iodophenyl)(6-chloropyridin-3-yl)methanone; 2-Chloro-5-(p-iodobenzoyl)pyridine; 6-Chloro-3-(4-iodobenzoyl)pyridine; 3-Pyridinecarbonyl chloride, 6-chloro-, 4-iodophenyl deriv.; 2-Chloro-5-(4-iodobenzoyl)pyridine; 1187170-32-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(4-Iodobenzoyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.