Description

2-(4-Bromo-2-Fluorophenyl)-3-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for enabling precise molecular modifications in the synthesis of active pharmaceutical ingredients (APIs) and other complex organic molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research and development.
• Agrochemical Synthesis: Used in the creation of advanced pesticides, herbicides, and fungicides where its halogenated structure provides specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic processes and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes for biological imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-(4-Bromo-2-Fluorophenyl)-3-Methylpyridine
CAS No.	1187169-99-8
Molecular Formula	C12H9BrFN
Molecular Weight	266.11 g/mol
Synonyms	3-Methyl-2-(4-bromo-2-fluorophenyl)pyridine; 2-(4-Bromo-2-fluorophenyl)-3-picoline; 4-Bromo-2-fluoro-α-(3-methyl-2-pyridinyl)benzene; 2-(4-Bromo-2-fluorophenyl)-3-methylpyridine; Pyridine, 2-(4-bromo-2-fluorophenyl)-3-methyl-; 1187169-99-8; 2-(4-Bromo-2-fluorophenyl)-3-methyl-pyridine
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Fluorophenyl)-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.