Description

4-(3,4-Dimethoxybenzoyl)-2-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoylpyridine structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific molecular framework serves as a key building block. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as an electron-transport or host material in the manufacture of high-performance OLED displays and lighting.
• Ligand for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for chemical research in medicinal chemistry and material science laboratories.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing complex, high-value specialty chemicals.

Basic Information

Product Name	4-(3,4-Dimethoxybenzoyl)-2-Methylpyridine
CAS No.	1187169-20-5
Molecular Formula	C15H15NO3
Molecular Weight	257.29 g/mol
Synonyms	2-Methyl-4-(3,4-dimethoxybenzoyl)pyridine; 4-(3,4-Dimethoxyphenyl)(2-methylpyridin-4-yl)methanone; Vericiguat Intermediate; BAY-1021189 Intermediate; Pyridine, 2-methyl-4-[(3,4-dimethoxyphenyl)carbonyl]-; (2-Methylpyridin-4-yl)(3,4-dimethoxyphenyl)methanone
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dimethoxybenzoyl)-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.