Description

4-Methyl-3-(3-Trifluoromethylbenzoyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethylbenzoyl-substituted pyridine structure. This compound is critical for research and development in medicinal chemistry, where its unique scaffold is leveraged to modulate the biological activity and pharmacokinetic properties of new chemical entities. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in areas such as kinase inhibitor development and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Kinase Inhibitor Research: Serves as a core scaffold in the development of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency, selectivity, and metabolic stability.
• CNS Drug Discovery: Employed in the research of compounds targeting neurological and psychiatric disorders due to its ability to cross the blood-brain barrier.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents with enhanced efficacy.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials.

Basic Information

Product Name	4-Methyl-3-(3-Trifluoromethylbenzoyl)Pyridine
CAS No.	1187168-61-1
Molecular Formula	C14H10F3NO
Molecular Weight	265.23 g/mol
Synonyms	3-(3-(Trifluoromethyl)benzoyl)-4-methylpyridine; 4-Methyl-3-[3-(trifluoromethyl)benzoyl]pyridine; 3-(3-Trifluoromethylbenzoyl)-4-methylpyridine; 4-Methyl-3-(3-trifluoromethylbenzoyl)pyridine; 1-(4-Methylpyridin-3-yl)-2-[3-(trifluoromethyl)phenyl]ethanone (tautomeric form); 3-Acetyl-4-methylpyridine, 3'-(trifluoromethyl) derivative
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(3-Trifluoromethylbenzoyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications, and our quality protocols are designed to meet the stringent requirements of global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.