Description

2-(3,4-Difluorobenzoyl)-5-Methylpyridine is a high-value, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its precise molecular architecture, which incorporates both a difluorinated benzoyl group and a methylpyridine moiety, enabling the fine-tuning of electronic and steric properties in target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique scaffold can impart enhanced metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a sophisticated building block for creating novel ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials that require fluorinated aromatic components for specific performance characteristics.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	2-(3,4-Difluorobenzoyl)-5-Methylpyridine
CAS No.	1187166-85-3
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	5-Methyl-2-(3,4-difluorobenzoyl)pyridine; (3,4-Difluorophenyl)(5-methylpyridin-2-yl)methanone; 2-(3,4-Difluorobenzoyl)-5-picoline; 5-Methyl-2-(3,4-difluorobenzoyl)pyridine; 1187166-85-3; Methanone, (3,4-difluorophenyl)(5-methyl-2-pyridinyl)-; SCHEMBL23802279
EINECS	Contact for details

Quality Control

Our 2-(3,4-Difluorobenzoyl)-5-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments, ensuring reliable supply for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.