Description

4-Methyl-2-(2-Trifluoromethylbenzoyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core substituted with a trifluoromethylbenzoyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring fluorinated compounds for improved drug efficacy and patent life.

Application

• Key intermediate in the synthesis of novel pharmaceutical candidates, especially kinase inhibitors and receptor antagonists.
• Building block for agrochemical research, contributing to the development of new herbicides and pesticides with fluorinated motifs.
• Precursor in material science for creating specialized ligands and functional organic molecules.
• Used in academic and industrial R&D for exploring structure-activity relationships (SAR) in drug discovery programs.
• Intermediate for the preparation of complex fluorinated heterocycles used in various high-value chemical syntheses.

Basic Information

Product Name	4-Methyl-2-(2-Trifluoromethylbenzoyl)Pyridine
CAS No.	1187165-17-8
Molecular Formula	C14H10F3NO
Molecular Weight	265.23 g/mol
Synonyms	2-(2-Trifluoromethylbenzoyl)-4-methylpyridine; 4-Methyl-2-(2-(trifluoromethyl)benzoyl)pyridine; 2-(α,α,α-Trifluoro-o-toluoyl)-4-picoline; 4-Methyl-2-(2-trifluoromethylbenzoyl)pyridine; 4-Methyl-2-(o-trifluoromethylbenzoyl)pyridine; 2-(2-Trifluoromethylbenzoyl)-4-picoline; 4-Picoline, 2-(2-(trifluoromethyl)benzoyl)-
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(2-Trifluoromethylbenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.