Description

5-(4-Bromo-2-Fluorophenyl)-2-Chloropyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile halogenated aromatic scaffold essential for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with tailored activity profiles.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce complex aryl groups.
• Chemical Biology: Utilized as a molecular probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis: A starting material for contract research organizations (CROs) and custom synthesis providers to manufacture bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	5-(4-Bromo-2-Fluorophenyl)-2-Chloropyridine
CAS No.	1187163-49-0
Molecular Formula	C11H6BrClFN
Molecular Weight	286.53 g/mol
Synonyms	2-Chloro-5-(4-bromo-2-fluorophenyl)pyridine; 5-(4-Bromo-2-fluorophenyl)-2-chloropyridine; 2-Chloro-5-(4-bromo-2-fluoro-phenyl)pyridine; (4-Bromo-2-fluorophenyl)-2-chloropyridine; 1187163-49-0; 5-(4-Bromo-2-fluorophenyl)-2-chloro-pyridine; 2-Chloro-5-(4'-bromo-2'-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-(4-Bromo-2-Fluorophenyl)-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.