Description

(2R,6S)-4-{4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Benzoyl}-2,6-Dimethylmorpholine is a high-purity, stereochemically defined organic compound designed for advanced pharmaceutical research and development. This molecule serves as a critical chiral building block or intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic targets. It is essential for medicinal chemists and process development scientists in pharmaceutical and biotechnology companies who require precise, high-quality intermediates to accelerate drug discovery pipelines and ensure robust manufacturing processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its defined stereochemistry and functionalized oxadiazole ring.
• Process Chemistry & Scale-up: Serves as a critical intermediate in the development and optimization of scalable synthetic routes for potential APIs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial drug substances.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and developing new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(2R,6S)-4-{4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Benzoyl}-2,6-Dimethylmorpholine
CAS No.	1186662-45-2
Molecular Formula	C17H20ClN3O3
Molecular Weight	349.81 g/mol
Synonyms	(2R,6S)-4-[4-(5-Chloromethyl-1,2,4-oxadiazol-3-yl)benzoyl]-2,6-dimethylmorpholine; 4-[4-(5-Chloromethyl-1,2,4-oxadiazol-3-yl)benzoyl]-2,6-dimethylmorpholine (2R,6S)-; (2R,6S)-4-(4-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)benzoyl)-2,6-dimethylmorpholine; UNII-3F1H8V2Q3R; 3F1H8V2Q3R; SCHEMBL2180621; AKOS025147065; (2R,6S)-rel-4-[4-(5-Chloromethyl-1,2,4-oxadiazol-3-yl)benzoyl]-2,6-dimethylmorpholine
EINECS	Contact for details

Quality Control

Our production of (2R,6S)-4-{4-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]Benzoyl}-2,6-Dimethylmorpholine adheres to stringent quality management systems, ensuring batch-to-batch consistency and high chemical purity suitable for research and development applications. Each batch is fully characterized and undergoes rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.