Description

3-Bromo-2-cyano-6-methoxypyridine is a versatile and high-value pyridine derivative used as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring bromine and cyano substituents on the pyridine ring, makes it an essential building block for constructing complex heterocyclic systems. This compound is particularly valuable for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is employed in cross-coupling reactions, nucleophilic substitutions, and as a precursor for functionalized pyridines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting compounds.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Scale-up: A fundamental substrate for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis for clients.

Basic Information

Product Name	3-Bromo-2-cyano-6-methoxypyridine
CAS No.	1186637-43-3
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	6-Methoxy-3-bromopyridine-2-carbonitrile; 3-Bromo-6-methoxypicolinonitrile; 2-Cyano-3-bromo-6-methoxypyridine; 3-Bromo-2-cyano-6-methoxypyridine; 1186637-43-3; 3-Bromo-6-methoxy-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-cyano-6-methoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.