Description

3-Methoxy-5-Nitro-1H-Pyrazolo[3,4-B]Pyridine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular scaffolds. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new drug candidates or high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its bioactive heterocyclic structure.
• Chemical Biology & Medicinal Chemistry: Employed as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Research: Investigated for the development of organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental organic synthesis and methodological development.

Basic Information

Product Name	3-Methoxy-5-Nitro-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1186614-21-0
Molecular Formula	C7H6N4O3
Molecular Weight	194.15 g/mol
Synonyms	3-Methoxy-5-nitropyrazolo[3,4-b]pyridine; 5-Nitro-3-methoxy-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-methoxy-5-nitro-; 3-Methoxy-5-nitro-1H-pyrazolo[3,4-b]pyridine; 1186614-21-0; 3-Methoxy-5-nitro-1H-pyrazolo[3,4-b]pyridine; 5-Nitro-3-methoxy-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Methoxy-5-Nitro-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.