Description

3-Iodo-5-Nitro-1H-Pyrazolo[3,4-B]Pyridine is a high-value, heterocyclic organic building block characterized by its fused pyrazolopyridine core functionalized with iodine and nitro groups. This compound matters as a versatile and reactive intermediate, enabling the synthesis of complex molecules for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for creating novel active ingredients, as well as by academic and industrial chemists exploring new materials and catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Acts as a precursor for the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine substituent, facilitating the construction of complex molecular architectures.
• Academic & Contract Research: A valuable reagent for methodological studies and the discovery of new chemical reactions in university and CRO laboratories.

Basic Information

Product Name	3-Iodo-5-Nitro-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1186609-70-0
Molecular Formula	C6H3IN4O2
Molecular Weight	290.01 g/mol
Synonyms	3-Iodo-5-nitropyrazolo[3,4-b]pyridine; 3-Iodo-5-nitro-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-iodo-5-nitro-; 5-Nitro-3-iodo-1H-pyrazolo[3,4-b]pyridine; 3-Iodo-5-nitro-1H-pyrazolo[3,4-b]pyridine; 1186609-70-0; 3-Iodo-5-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 1186609-70-0)
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Nitro-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.