Description

(3S,8As)-3-((S)-sec-Butyl)-Hexahydropyrrolo(1,2-A)Pyrazine is a high-purity, stereochemically defined chiral building block and pharmaceutical intermediate. This compound matters for its precise three-dimensional structure, which is critical for imparting specific biological activity and selectivity in advanced drug molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutics, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or organocatalysts.
• Peptidomimetic Chemistry: Utilized in the design and synthesis of molecules that mimic peptide structures for enhanced stability and bioavailability.

Basic Information

Product Name	(3S,8As)-3-((S)-sec-Butyl)-Hexahydropyrrolo(1,2-A)Pyrazine
CAS No.	1186497-15-3
Molecular Formula	C11H20N2
Molecular Weight	180.29 g/mol
Synonyms	(3S,8aS)-3-[(2S)-Butan-2-yl]octahydropyrrolo[1,2-a]pyrazine; Hexahydropyrrolo[1,2-a]pyrazine, 3-[(1S)-1-methylpropyl]-, (3S,8aS)-; (3S,8aS)-3-((S)-sec-Butyl)octahydropyrrolo[1,2-a]pyrazine; (S,S)-3-sec-Butyl-hexahydropyrrolo[1,2-a]pyrazine; Chiral Pyrrolopyrazine Derivative; CAS 1186497-15-3
EINECS	Contact for details

Quality Control

Our (3S,8As)-3-((S)-sec-Butyl)-Hexahydropyrrolo(1,2-A)Pyrazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.