Description

(E)-Methyl 3-(2-Chloro-3-(Dimethoxymethyl)Pyridin-4-Yl)Acrylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine-acrylate structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile building block for cross-coupling and cyclization reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used as a precursor for developing advanced herbicides and fungicides with specific modes of action.
• Chemical Research: Serves as a versatile building block in organic synthesis for constructing complex heterocyclic frameworks.
• Material Science: Potential monomer or precursor for specialty polymers and functional materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(E)-Methyl 3-(2-Chloro-3-(Dimethoxymethyl)Pyridin-4-Yl)Acrylate
CAS No.	1186405-24-2
Molecular Formula	C₁₂H₁₄ClNO₄
Molecular Weight	271.70 g/mol
Synonyms	Methyl (2E)-3-[2-Chloro-3-(dimethoxymethyl)-4-pyridinyl]-2-propenoate; (E)-Methyl 3-(2-Chloro-3-(dimethoxymethyl)-4-pyridinyl)acrylate; 2-Propenoic acid, 3-[2-chloro-3-(dimethoxymethyl)-4-pyridinyl]-, methyl ester, (2E)-; Methyl (E)-3-(2-chloro-3-(dimethoxymethyl)pyridin-4-yl)acrylate; 4-Pyridineacrylic acid derivative
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(2-Chloro-3-(Dimethoxymethyl)Pyridin-4-Yl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.