Description

2-(Trimethylsilyl)Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime is a specialized organosilicon heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique fused ring system and functional groups enable complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its structural motifs can contribute to biological activity and selectivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) or semiconductors, due to its conjugated furopyridine system.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis, where the oxime and silyl groups can be further functionalized to modulate metal coordination.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic routes involving silyl-protected heterocycles.

Basic Information

Product Name	2-(Trimethylsilyl)Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime
CAS No.	1186405-19-5
Molecular Formula	C14H18N2O2Si
Molecular Weight	274.40 g/mol
Synonyms	6-Formyl-2-(trimethylsilyl)furo[3,2-b]pyridine oxime; 2-(Trimethylsilyl)-6-(hydroxyiminomethyl)furo[3,2-b]pyridine; Furo[3,2-b]pyridine-6-carbaldehyde, 2-(trimethylsilyl)-, oxime; TMS-Furopyridine Oxime; 1186405-19-5; (2-(Trimethylsilyl)furo[3,2-b]pyridin-6-yl)methanone oxime
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsilyl)Furo[3,2-B]Pyridine-6-Carbaldehyde Oxime is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.