Description

Methyl 8-Chloro-6-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-7-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique trifluoromethyl and chloro-substituted imidazopyridine scaffold enables the creation of novel bioactive molecules. It is primarily sought after by medicinal chemists and process development scientists for constructing complex molecular architectures with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the imidazopyridine core.
• Material Science: Serves as a specialized monomer or additive in the research of advanced organic electronic materials and liquid crystals.
• Chemical Biology: Employed as a molecular probe or scaffold in drug discovery for studying protein-ligand interactions and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 8-Chloro-6-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-7-Carboxylate
CAS No.	1186405-14-0
Molecular Formula	C10H5ClF3N2O2
Molecular Weight	278.61 g/mol
Synonyms	Methyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carboxylate; 8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carboxylic acid methyl ester; Imidazo[1,2-a]pyridine-7-carboxylic acid, 8-chloro-6-(trifluoromethyl)-, methyl ester; 1186405-14-0; Methyl 8-chloro-6-trifluoromethylimidazo[1,2-a]pyridine-7-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 8-Chloro-6-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-7-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.