Description

2-Chloro-3-Iodo-4-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring chlorine, iodine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used to develop next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and halogen groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a sophisticated scaffold for creating novel ligands in transition metal catalysis and organocatalysis, enabling challenging chemical transformations.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring precise halogenated intermediates.

Basic Information

Product Name	2-Chloro-3-Iodo-4-(Trifluoromethyl)Pyridine
CAS No.	1186405-09-3
Molecular Formula	C7H2ClF3IN
Molecular Weight	321.45 g/mol
Synonyms	2-Chloro-3-iodo-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-chloro-3-iodopyridine; 3-Iodo-2-chloro-4-trifluoromethylpyridine; Pyridine, 2-chloro-3-iodo-4-(trifluoromethyl)-; 2-Chloro-3-iodo-4-trifluoromethylpyridine; 1186405-09-3; 2-Chloro-3-iodo-4-(trifluoromethyl)pyridine (CAS 1186405-09-3)
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Iodo-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP (Good Manufacturing Practice) environments and research requiring the highest material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.