Description

n-(3-Hydroxy-2-Iodopyridin-4-Yl)Acetamide is a high-purity iodinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a functionalized, halogenated heterocycle into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the iodopyridine scaffold can impart specific biological activity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to the reactivity of the iodine atom.
• Material Science: Potential intermediate for synthesizing organic electronic materials or liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.

Basic Information

Product Name	n-(3-Hydroxy-2-Iodopyridin-4-Yl)Acetamide
CAS No.	1186310-97-3
Molecular Formula	C7H7IN2O2
Molecular Weight	278.05 g/mol
Synonyms	4-Acetamido-3-hydroxy-2-iodopyridine; 2-Iodo-3-hydroxypyridin-4-ylacetamide; N-(3-Hydroxy-2-iodo-4-pyridinyl)acetamide; Acetamide, N-(3-hydroxy-2-iodo-4-pyridinyl)-; 4-Pyridineacetamide, 3-hydroxy-2-iodo-; 1186310-97-3; 2-Iodo-3-hydroxypyridine-4-carboxamide (related); 4-Acetylamino-3-hydroxy-2-iodopyridine
EINECS	Contact for details

Quality Control

Our n-(3-Hydroxy-2-Iodopyridin-4-Yl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.