Description

(R)-tert-Butyl 3-(Pyrazin-2-Ylamino)Pyrrolidine-1-Carboxylate CAS NO 1186299-89-7 is a high-purity, chiral pyrrolidine derivative serving as a critical building block in modern pharmaceutical synthesis. This compound matters because it provides a sophisticated, enantiomerically pure scaffold essential for constructing complex molecules with specific biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex target molecules, leveraging its pyrrolidine and pyrazine functional groups.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions due to its enantiomeric purity.
• Ligand and Catalyst Development: Potential precursor for designing novel chiral ligands and organocatalysts.
• Preclinical & Clinical Trial Material: Supplied under GMP guidelines for the production of materials used in non-clinical and clinical studies.

Basic Information

Product Name	(R)-tert-Butyl 3-(Pyrazin-2-Ylamino)Pyrrolidine-1-Carboxylate
CAS No.	1186299-89-7
Molecular Formula	C13H20N4O2
Molecular Weight	264.33 g/mol
Synonyms	1-Boc-3-(pyrazin-2-ylamino)-(R)-pyrrolidine; (R)-1-(tert-Butoxycarbonyl)-3-(pyrazin-2-ylamino)pyrrolidine; tert-Butyl (3R)-3-(pyrazin-2-ylamino)pyrrolidine-1-carboxylate; (R)-N-Boc-3-amino-3-(2-pyrazinyl)pyrrolidine; BOC-(R)-3-(2-Pyrazinylamino)pyrrolidine; 1-Boc-3-(2-pyrazinylamino)-(R)-pyrrolidine; (R)-tert-Butyl 3-((pyrazin-2-yl)amino)pyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-(Pyrazin-2-Ylamino)Pyrrolidine-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and material can be supplied under GMP conditions for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.