Description

2-Methyl-5-(Trifluoromethyl)Pyrazine is a high-purity, fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group, imparts valuable properties such as enhanced metabolic stability and lipophilicity to target molecules. This specialized intermediate is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients. The compound is supplied with full traceability and comprehensive analytical documentation to support rigorous quality requirements.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Investigated as a monomer or additive for developing specialty polymers and advanced materials with specific electronic or surface properties.
• Flavor & Fragrance Chemistry: Employed in the synthesis of complex aroma chemicals, contributing nutty, roasted, or pyrazine-type olfactory notes to fragrance compositions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Pyrazine
CAS No.	1186195-51-6
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	5-(Trifluoromethyl)-2-methylpyrazine; 2-Methyl-5-trifluoromethylpyrazine; Pyrazine, 2-methyl-5-(trifluoromethyl)-; 2-Methyl-5-(trifluoromethyl)-1,4-diazine
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-(Trifluoromethyl)Pyrazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure the material meets the precise requirements of your application. Our standard quality commitment includes HPLC purity ≥98.0% (area percentage), with detailed impurity profiling available. A Certificate of Analysis (COA) containing batch-specific data for identity, assay, and purity is supplied with each shipment. Custom synthesis and specific purity grades (e.g., >99%) can be accommodated upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.