Description

2-Bromo-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxaldehyde is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique bromo-aldehyde functionality, which enables precise derivatization and serves as a key precursor in constructing complex molecular architectures. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials research sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for target identification and validation.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Nucleophilic Substitution & Condensation: The reactive aldehyde group facilitates condensation reactions (e.g., with amines, hydrazines) for heterocycle formation.

Basic Information

Product Name	2-Bromo-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxaldehyde
CAS No.	1185428-32-3
Molecular Formula	C7H4BrN3O
Molecular Weight	226.03 g/mol
Synonyms	2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde; 7-Bromo-3H-pyrrolo[2,3-b]pyrazine-5-carboxaldehyde; 2-Bromo-7-formyl-5H-pyrrolo[2,3-b]pyrazine; 1185428-32-3; 2-Bromo-5H-pyrrolo[2,3-b]pyrazine-7-carboxaldehyde; Pyrrolo[2,3-b]pyrazine-7-carboxaldehyde, 2-bromo-5H-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5H-Pyrrolo[2,3-B]Pyrazine-7-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.