Description

4-((3-Hydroxypiperidin-1-Yl)Methyl)-N,n-Dimethylbenzenesulfonamide, 98+% C14H22N2O3S, Mw: 298.40 is a high-purity, functionalized sulfonamide derivative with a piperidine moiety, serving as a critical pharmaceutical intermediate and research chemical. Its molecular structure, featuring both a sulfonamide group and a hydroxypiperidine ring, makes it a valuable scaffold for medicinal chemistry, particularly in the development of enzyme inhibitors and receptor modulators. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors, where precise chemical building blocks are required for drug discovery and synthesis. CAS No. 1185320-06-2.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Protease & Enzyme Inhibitor Development: The sulfonamide group is instrumental in creating potential inhibitors for various enzymes, including carbonic anhydrases and proteases.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the optimization and pilot-scale production of candidate drugs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	4-((3-Hydroxypiperidin-1-Yl)Methyl)-N,n-Dimethylbenzenesulfonamide, 98+%
CAS No.	1185320-06-2
Molecular Formula	C14H22N2O3S
Molecular Weight	298.40 g/mol
Synonyms	N,N-Dimethyl-4-[(3-hydroxypiperidin-1-yl)methyl]benzenesulfonamide; 4-[(3-Hydroxy-1-piperidinyl)methyl]-N,N-dimethylbenzenesulfonamide; 1-[4-(Dimethylsulfamoyl)benzyl]piperidin-3-ol; 1185320-06-2; Benzenesulfonamide, 4-((3-hydroxy-1-piperidinyl)methyl)-N,N-dimethyl-; 4-[(3-Hydroxypiperidin-1-yl)methyl]-N,N-dimethylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Every batch of our 4-((3-Hydroxypiperidin-1-Yl)Methyl)-N,n-Dimethylbenzenesulfonamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.