Description

1-(5-Nitropyridin-2-Yl)-Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its nitropyridine-piperazine core structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D laboratories and pharmaceutical manufacturers in the development of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry R&D: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a building block for creating libraries of novel heterocyclic compounds for high-throughput screening.
• Academic Research: Employed in university and institutional labs for studying reaction mechanisms and developing new synthetic methodologies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug development and custom synthesis projects.

Basic Information

Product Name	1-(5-Nitropyridin-2-Yl)-Piperazine Hydrochloride
CAS No.	1185319-62-3
Molecular Formula	C9H13ClN4O2
Molecular Weight	244.68 g/mol
Synonyms	1-(5-Nitropyridin-2-yl)piperazine hydrochloride; 2-(1-Piperazinyl)-5-nitropyridine hydrochloride; 5-Nitro-2-piperazin-1-ylpyridine hydrochloride; Piperazine, 1-(5-nitro-2-pyridinyl)-, hydrochloride (1:1); 1185319-62-3
EINECS	Contact for details

Quality Control

Our 1-(5-Nitropyridin-2-Yl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.