Description

2-(Piperidin-3-Yloxy)-Pyrazine Hydrochloride is a high-purity organic salt with the molecular formula C9H14ClN3O and a molecular weight of 215.68. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and other therapeutic targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its piperidine and pyrazine motifs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme function or receptor interactions.
• Process Chemistry: Employed in route scouting and scale-up synthesis for Active Pharmaceutical Ingredient (API) manufacturing.
• Academic Research: Utilized in university and institutional labs for organic synthesis projects and novel heterocyclic compound development.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for clients.

Basic Information

Item	Details
Product Name	2-(Piperidin-3-Yloxy)-Pyrazine Hydrochloride
CAS No.	1185312-42-8
Molecular Formula	C9H14ClN3O
Molecular Weight	215.68 g/mol
Synonyms	2-[(3-Piperidinyl)oxy]pyrazine hydrochloride; 2-(Piperidin-3-yloxy)pyrazine HCl; Pyrazine, 2-(3-piperidinyloxy)-, hydrochloride; 3-(Pyrazin-2-yloxy)piperidine hydrochloride; 1185312-42-8; 2-(3-Piperidyloxy)pyrazine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-3-Yloxy)-Pyrazine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets the 98+% purity specification and is free from critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other key parameters. Our quality commitment aligns with standards expected for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.