Description

(3-Hydroxy-Piperidin-1-Yl)-Pyrazin-2-Yl-Methanone Hydrochloride is a high-purity, non-natural amino acid derivative and a key heterocyclic building block used in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, offering a versatile scaffold for creating novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Peptidomimetic Synthesis: Acts as a constrained, heterocyclic amino acid analog for creating novel peptide-like compounds with enhanced stability and bioavailability.
• Ligand Synthesis for Catalysis: Can be utilized to develop novel chiral ligands for asymmetric catalysis in fine chemical production.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(3-Hydroxy-Piperidin-1-Yl)-Pyrazin-2-Yl-Methanone Hydrochloride
CAS No.	1185309-06-1
Molecular Formula	C10H14ClN3O2
Molecular Weight	243.69 g/mol
Synonyms	1-(Pyrazin-2-ylcarbonyl)-3-hydroxypiperidine hydrochloride; 3-Hydroxy-1-(pyrazine-2-carbonyl)piperidine hydrochloride; (3-Hydroxypiperidin-1-yl)(pyrazin-2-yl)methanone hydrochloride; 2-[(3-Hydroxy-1-piperidinyl)carbonyl]pyrazine hydrochloride; 3-Hydroxy-N-(pyrazin-2-yl)piperidine-1-carboxamide hydrochloride (tautomeric form); 3-Hydroxypiperidine-1-pyrazinyl ketone hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Hydroxy-Piperidin-1-Yl)-Pyrazin-2-Yl-Methanone Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) documenting identity, purity (98+%), and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.