Description

1-[1-(3-Chloro-Phenyl)-Ethyl]-Piperazine Hydrochloride is a high-purity, synthetically derived piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile chiral scaffold for constructing complex molecules with targeted pharmacological properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its piperazine core for biological activity.
• Chemical Synthesis: Serves as a versatile building block for creating complex amines and heterocyclic compounds in medicinal chemistry.
• Academic & R&D: Employed in university and contract research laboratories for method development and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and APIs.

Basic Information

Product Name	1-[1-(3-Chloro-Phenyl)-Ethyl]-Piperazine Hydrochloride
CAS No.	1185307-54-3
Molecular Formula	C12H17ClN2·HCl
Molecular Weight	261.19 g/mol
Synonyms	1-[1-(3-Chlorophenyl)ethyl]piperazine hydrochloride; (R/S)-1-[1-(3-Chlorophenyl)ethyl]piperazine hydrochloride; 3-Chloro-α-methylbenzylpiperazine hydrochloride; 1-(1-(3-Chlorophenyl)ethyl)piperazine HCl; 1-(3-Chloro-α-methylbenzyl)piperazine hydrochloride; m-Chloro-α-methylbenzylpiperazine HCl
EINECS	Contact for details

Quality Control

Our 1-[1-(3-Chloro-Phenyl)-Ethyl]-Piperazine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) confirming identity, purity, and specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.