Description

3-[4-(2-Hydroxy-Ethyl)-Piperazin-1-Yl]-Propionic Acid 2Hcl is a high-purity organic salt derivative of piperazine, valued for its role as a versatile synthetic intermediate and building block. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of complex active pharmaceutical ingredients (APIs). It is primarily needed by fine chemical manufacturers, pharmaceutical R&D laboratories, and academic institutions engaged in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• API Development: Used in research and process development for new Active Pharmaceutical Ingredients (APIs).
• Ligand Synthesis: Serves as a precursor for creating chelating agents and ligands used in catalysis and metal complexation.
• Bioconjugation Chemistry: Utilized in the development of linkers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with tailored properties.
• Academic & Industrial Research: Employed in chemical libraries and for exploring new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	3-[4-(2-Hydroxy-Ethyl)-Piperazin-1-Yl]-Propionic Acid 2Hcl
CAS No.	1185300-58-6
Molecular Formula	C9H20Cl2N2O3
Molecular Weight	275.17 g/mol
Synonyms	2-(4-(2-Carboxyethyl)piperazin-1-yl)ethanol dihydrochloride; 3-(4-(2-Hydroxyethyl)piperazin-1-yl)propanoic acid dihydrochloride; 1-(2-Hydroxyethyl)-4-(2-carboxyethyl)piperazine dihydrochloride; HEPP dihydrochloride; N-(2-Hydroxyethyl)piperazine-N'-propionic acid dihydrochloride; 2-[4-(2-Carboxyethyl)-1-piperazinyl]ethanol dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-[4-(2-Hydroxy-Ethyl)-Piperazin-1-Yl]-Propionic Acid 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.