Description

Ethyl 4-(3-Methylpiperazin-1-Yl)-3-Nitrobenzoate Hydrochloride is a high-purity, non-GMP organic salt of significant interest in advanced chemical synthesis. This compound matters as a critical pharmaceutical intermediate and research chemical for developing novel active molecules. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Reference Standard: Employed as an analytical standard for quality control and method development in HPLC and LC-MS analysis.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 4-(3-Methylpiperazin-1-Yl)-3-Nitrobenzoate Hydrochloride
CAS No.	1185298-87-6
Molecular Formula	C14H20N3O4 • HCl
Molecular Weight	327.79 g/mol (Free base: 291.33 g/mol)
Synonyms	4-(3-Methyl-1-piperazinyl)-3-nitrobenzoic acid ethyl ester hydrochloride; Ethyl 4-(3-methylpiperazin-1-yl)-3-nitrobenzoate HCl; 3-Nitro-4-(3-methyl-1-piperazinyl)benzoic acid ethyl ester hydrochloride; Benzoic acid, 4-(3-methyl-1-piperazinyl)-3-nitro-, ethyl ester, hydrochloride; Ethyl 3-nitro-4-(3-methylpiperazin-1-yl)benzoate hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3-Methylpiperazin-1-Yl)-3-Nitrobenzoate Hydrochloride is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and residual solvents. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.