Description

1-[4-Nitro-3-(Trifluoromethyl)Phenyl]Homopiperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and nitro-substituted aromatic structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Chemical Biology Probe: Serves as a precursor for creating specialized probes to study enzyme inhibition and receptor binding mechanisms.
• Material Science Research: Investigated for incorporation into advanced polymers or liquid crystals due to its aromatic and heterocyclic components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-[4-Nitro-3-(Trifluoromethyl)Phenyl]Homopiperazine Hydrochloride
CAS No.	1185298-60-5
Molecular Formula	C13H15F3N4O2·HCl
Molecular Weight	351.74 g/mol
Synonyms	1-[4-Nitro-3-(trifluoromethyl)phenyl]hexahydro-1H-1,4-diazepine hydrochloride; 1-(4-Nitro-3-trifluoromethylphenyl)homopiperazine hydrochloride; 1-(4-Nitro-3-(trifluoromethyl)phenyl)-1,4-diazepane hydrochloride; Homopiperazine, 1-[4-nitro-3-(trifluoromethyl)phenyl]-, hydrochloride; UNII-6Q8Q3G2P8T; 6Q8Q3G2P8T
EINECS	Contact for details

Quality Control

Our 1-[4-Nitro-3-(Trifluoromethyl)Phenyl]Homopiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.