Description

3-Piperazin-1-Ylmethyl-Benzamide Dihydrochloride is a high-purity chemical building block and research compound. This dihydrochloride salt form offers enhanced stability and solubility for advanced chemical synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its piperazine and benzamide functional groups.
• Biochemical Research: Employed as a reference standard or tool compound in pharmacological assays and target validation studies.
• Process Chemistry: Serves as a starting material or intermediate in scale-up and route development for GMP manufacturing.
• Academic Research: Utilized in university and institutional laboratories for organic synthesis projects and the study of heterocyclic chemistry.

Basic Information

Product Name	3-Piperazin-1-Ylmethyl-Benzamide Dihydrochloride
CAS No.	1185298-28-5
Molecular Formula	C12H18N4O · 2HCl
Molecular Weight	307.22 g/mol (free base: 234.30 g/mol)
Synonyms	3-[(Piperazin-1-yl)methyl]benzamide dihydrochloride; 3-(Piperazin-1-ylmethyl)benzamide dihydrochloride; Benzamide, 3-[(1-piperazinyl)methyl]-, dihydrochloride; 3-Piperazin-1-ylmethyl-benzamide 2HCl; 3-(Piperazin-1-ylmethyl)benzamide hydrochloride (1:2); 1185298-28-5; UNII-9C2V7Q3V6I
EINECS	Contact for details

Quality Control

Our 3-Piperazin-1-Ylmethyl-Benzamide Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.