Description

2-[4-(4-Fluoro-2-Nitrophenyl)Piperazin-1-Yl]Ethanol Hydrochloride is a high-purity, synthetically derived chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly in the pharmaceutical research and development sector. This compound is essential for medicinal chemists and process development scientists working on novel therapeutics, especially within central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used as a core scaffold or building block in structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound Synthesis: Employed in the development of receptor ligands and other probes for biological research.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	2-[4-(4-Fluoro-2-Nitrophenyl)Piperazin-1-Yl]Ethanol Hydrochloride
CAS No.	1185297-30-6
Molecular Formula	C12H15FN3O3 • HCl
Molecular Weight	289.72 g/mol (Free base: 253.27 g/mol)
Synonyms	1-(2-Hydroxyethyl)-4-(4-fluoro-2-nitrophenyl)piperazine hydrochloride; 4-(4-Fluoro-2-nitrophenyl)-1-piperazineethanol hydrochloride; 2-[4-(4-Fluoro-2-nitrophenyl)-1-piperazinyl]ethanol hydrochloride; 2-(4-(4-Fluoro-2-nitrophenyl)piperazin-1-yl)ethan-1-ol hydrochloride; 1-(4-Fluoro-2-nitrophenyl)-4-(2-hydroxyethyl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Fluoro-2-Nitrophenyl)Piperazin-1-Yl]Ethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened only in a dry environment.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.