Description

n-[(1-Methylpiperidin-4-Yl)Methyl]-2-Phenylethanamine Dihydrochloride is a high-purity, specialized organic salt primarily utilized as a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and receptor-based pathways. It is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and receptor modulator research.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Potential use in the development of biochemical probes and tools for studying specific enzymatic or receptor interactions.

Basic Information

Product Name	n-[(1-Methylpiperidin-4-Yl)Methyl]-2-Phenylethanamine Dihydrochloride
CAS No.	1185293-42-8
Molecular Formula	C15H24N2·2HCl
Molecular Weight	297.28 g/mol (free base: 232.37 g/mol)
Synonyms	2-Phenylethanamine, N-[(1-methyl-4-piperidinyl)methyl]-, dihydrochloride; N-[(1-Methylpiperidin-4-yl)methyl]-2-phenylethan-1-amine dihydrochloride; 1-Methyl-4-[(2-phenylethylamino)methyl]piperidine dihydrochloride; 1185293-42-8; (1-Methyl-4-piperidinyl)methyl(2-phenylethyl)amine dihydrochloride
EINECS	Contact for details

Quality Control

Our n-[(1-Methylpiperidin-4-Yl)Methyl]-2-Phenylethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.