Description

α-[(2-Methoxyphenoxy)Methyl]-1-Piperazineethanol Dihydrochloride is a high-purity, functionalized piperazine derivative supplied as a dihydrochloride salt. This compound is a critical building block in pharmaceutical research and development, offering a versatile scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of central nervous system (CNS) and cardiovascular drug candidates.
• Chemical Synthesis Building Block: Used to introduce the piperazineethanol moiety into larger molecular architectures for structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a starting material for the synthesis of novel crop protection agents and herbicides.
• Bioconjugation & Probe Development: Utilized in medicinal chemistry for creating labeled compounds and biochemical probes.
• Academic & Institutional Research: Employed in university and contract research organization (CRO) laboratories for exploratory synthetic chemistry.
• Process Chemistry & Scale-Up: Suitable for use in route scouting and optimization for pilot-scale and commercial manufacturing.

Basic Information

Product Name	α-[(2-Methoxyphenoxy)Methyl]-1-Piperazineethanol Dihydrochloride
CAS No.	1185293-30-4
Molecular Formula	C14H23Cl2N2O3
Molecular Weight	335.25 g/mol
Synonyms	1-Piperazineethanol, α-[(2-methoxyphenoxy)methyl]-, dihydrochloride; 2-[(2-Methoxyphenoxy)methyl]-2-(piperazin-1-yl)ethanol dihydrochloride; 2-(Piperazin-1-yl)-2-[(2-methoxyphenoxy)methyl]ethanol dihydrochloride; UNII-9J7Q2S4F3R; 9J7Q2S4F3R; α-(2-Methoxyphenoxymethyl)-1-piperazineethanol dihydrochloride; (RS)-α-[(2-Methoxyphenoxy)methyl]-1-piperazineethanol dihydrochloride
EINECS	Contact for details

Quality Control

Our α-[(2-Methoxyphenoxy)Methyl]-1-Piperazineethanol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.