Description

1,4'-Bipiperidine-3-Carboxylic Acid Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in advanced chemical synthesis. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other complex molecules. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis or biochemical studies.
• Chemical Biology Probes: Incorporated into molecular probes for investigating biological pathways and target identification.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	1,4'-Bipiperidine-3-Carboxylic Acid Dihydrochloride
CAS No.	1185293-24-6
Molecular Formula	C11H20N2O2 • 2HCl
Molecular Weight	293.21 g/mol (Free base: 212.29)
Synonyms	3-(Piperidin-4-yl)piperidine-4-carboxylic acid dihydrochloride; 1,4'-Bipiperidine-3-carboxylic acid hydrochloride (1:2); 4-(Piperidin-4-yl)piperidine-3-carboxylic acid dihydrochloride; 1,4'-Diaza-3-carboxybicyclo[4.4.0]decane dihydrochloride; Bipiperidine carboxylic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our 1,4'-Bipiperidine-3-Carboxylic Acid Dihydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.