Description

1-Methylpiperazin-2-One Dihydrochloride is a high-purity, pharmaceutically relevant salt form of a key heterocyclic building block. This compound matters as a versatile intermediate in the synthesis of complex molecules, offering critical structural motifs for medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging its heterocyclic piperazine core.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex molecular libraries in combinatorial chemistry and medicinal chemistry programs.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other advanced chemical transformations.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of high-value, specialty fine chemicals and performance materials.

Basic Information

Product Name	1-Methylpiperazin-2-One Dihydrochloride
CAS No.	1185292-91-4
Molecular Formula	C5H12Cl2N2O
Molecular Weight	199.07 g/mol
Synonyms	1-Methyl-2-piperazinone dihydrochloride; 1-Methylpiperazin-2-one hydrochloride (1:2); 2-Piperazinone, 1-methyl-, dihydrochloride; 1-Methyl-2-oxopiperazine dihydrochloride; N-Methyl-2-oxopiperazine dihydrochloride; 1-Methyl-2-ketopiperazine dihydrochloride; 1-Methylpiperazine-2-one dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Methylpiperazin-2-One Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.