Description

3-(4-Fluorophenyl) Morpholine Hydrochloride is a high-purity, fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the morpholine and fluorophenyl motifs are critical for modulating biological activity and physicochemical properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors engaged in drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and stability.
• Chemical Research & Development: A valuable reagent for medicinal chemists exploring structure-activity relationships (SAR) and for creating novel chemical libraries.
• Ligand and Catalyst Preparation: Can be utilized to synthesize complex ligands for catalysis or as a precursor for functional materials.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-(4-Fluorophenyl) Morpholine Hydrochloride
CAS No.	1185045-95-7
Molecular Formula	C10H12FNO•HCl
Molecular Weight	217.67 g/mol
Synonyms	3-(4-Fluorophenyl)morpholine hydrochloride; 4-(4-Fluorophenyl)morpholin-3-one hydrochloride (tautomer); 4-Fluorophenylmorpholine HCl; Morpholine, 3-(4-fluorophenyl)-, hydrochloride; 1185045-95-7; 3-(p-Fluorophenyl)morpholine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl) Morpholine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.