Description

(4-Benzylpiperazin-1-Yl)Piperidin-4-Yl-Methanone Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies seeking reliable, high-quality intermediates for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in pharmacological research to study receptor-ligand interactions and signal transduction pathways.
• Fine Chemical Synthesis: Serves as a building block for the custom synthesis of complex organic molecules for specialized applications.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(4-Benzylpiperazin-1-Yl)Piperidin-4-Yl-Methanone Dihydrochloride
CAS No.	1185013-84-6
Molecular Formula	C18H28N3O·2HCl
Molecular Weight	379.35 g/mol (Free base: 302.44 g/mol)
Synonyms	4-[(4-Benzyl-1-piperazinyl)carbonyl]piperidine dihydrochloride; 1-Benzyl-4-(4-piperidinylcarbonyl)piperazine dihydrochloride; (4-Benzylpiperazin-1-yl)(piperidin-4-yl)methanone dihydrochloride; 4-(4-Benzylpiperazine-1-carbonyl)piperidine dihydrochloride; BPMC Dihydrochloride; Piperidine-4-carboxylic acid (4-benzyl-piperazin-1-yl)-amide dihydrochloride
EINECS	Contact for details

Quality Control

Our (4-Benzylpiperazin-1-Yl)Piperidin-4-Yl-Methanone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D and GMP-grade intermediate production. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.