Description

1-Phenyl-4-[(Piperidin-4-Yl)Carbonyl]Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a well-defined piperazine-piperidine scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• Ligand Synthesis: Serves as a precursor for the development of ligands targeting specific receptors (e.g., serotonin, dopamine receptors) in the CNS.
• Chemical Library Production: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Reference Standard: Used as an analytical standard in quality control and method development for related pharmaceutical processes.

Basic Information

Product Name	1-Phenyl-4-[(Piperidin-4-Yl)Carbonyl]Piperazine Hydrochloride
CAS No.	1184996-07-3
Molecular Formula	C16H23N3O·HCl
Molecular Weight	309.84 g/mol
Synonyms	1-Phenyl-4-(piperidine-4-carbonyl)piperazine hydrochloride; 4-(4-Phenylpiperazine-1-carbonyl)piperidine hydrochloride; N-(1-Phenylpiperazin-4-yl)piperidine-4-carboxamide hydrochloride; Piperazine, 1-phenyl-4-(4-piperidinylcarbonyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-Phenyl-4-[(Piperidin-4-Yl)Carbonyl]Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.