Description

3-Amino-4-Fluoro-1-Piperidinecarboxylic Acid Benzyl Ester is a high-purity, fluorinated piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a protected carboxylic acid and a reactive amino group, makes it an invaluable intermediate for constructing complex pharmacophores. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the areas of medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in protease inhibitor and central nervous system (CNS) active compound research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new therapeutic avenues.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides and pesticides with enhanced efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Peptidomimetic Development: The benzyl ester and amino functionality make it suitable for constructing peptide analogs and mimetics.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, fluorinated piperidine scaffolds.

Basic Information

Product Name	3-Amino-4-Fluoro-1-Piperidinecarboxylic Acid Benzyl Ester
CAS No.	1184920-12-4
Molecular Formula	C13H17FN2O2
Molecular Weight	252.29 g/mol
Synonyms	Benzyl 3-Amino-4-fluoropiperidine-1-carboxylate; 1-(Benzyloxycarbonyl)-3-amino-4-fluoropiperidine; 4-Fluoro-3-aminopiperidine-1-carboxylic acid benzyl ester; 3-Amino-4-fluoro-N-Cbz-piperidine; Z-3-Amino-4-fluoropiperidine; 3-Amino-4-fluoropiperidine-1-carboxylic acid benzyl ester; 1-CBZ-3-AMINO-4-FLUOROPIPERIDINE; 4-Fluoro-3-aminopiperidine-1-carboxylate benzyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Fluoro-1-Piperidinecarboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.