Description

1-Isopropyl-5-Oxopyrrolidine-3-Carbonyl Chloride is a high-purity, reactive chemical intermediate designed for advanced synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing novel pyrrolidinone-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the pyrrolidinone pharmacophore.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic structures for efficacy.
• Organic Synthesis: Serves as a versatile acyl chloride reagent for introducing the 1-isopropyl-5-oxopyrrolidine-3-carbonyl moiety into more complex molecular architectures.
• Peptidomimetics Development: Employed in medicinal chemistry for creating protease inhibitors and other drug candidates that mimic peptide structures.
• Material Science Precursor: Potential use in synthesizing specialized polymers or ligands for catalytic systems.

Basic Information

Product Name	1-Isopropyl-5-Oxopyrrolidine-3-Carbonyl Chloride
CAS No.	1181455-29-7
Molecular Formula	C9H12ClNO2
Molecular Weight	201.65 g/mol
Synonyms	1-Isopropyl-5-oxopyrrolidine-3-carbonyl chloride; 3-Pyrrolidinecarbonyl chloride, 1-(1-methylethyl)-2,5-dihydro-1H-pyrrol-2-one; 1-(Propan-2-yl)-5-oxopyrrolidine-3-carbonyl chloride; 5-Oxo-1-(propan-2-yl)pyrrolidine-3-carbonyl chloride; 1-Isopropyl-2,5-dihydro-1H-pyrrole-2,5-dione-3-carbonyl chloride (tautomeric form); Proline derivative, acyl chloride; Isopropyl pyrrolidinone carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-5-Oxopyrrolidine-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.