Description

1-n-Cbz-2-n-Propylpiperazine-Hcl is a high-purity, protected piperazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing complex molecular architectures, particularly in the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, particularly those containing a piperazine core.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Serves as a building block for creating peptide analogs and mimetics due to its protected amine functionality.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional laboratories for methodological development and exploratory synthesis.

Basic Information

Product Name	1-n-Cbz-2-n-Propylpiperazine-Hcl
CAS No.	1179361-53-5
Molecular Formula	C15H23ClN2O2
Molecular Weight	298.81 g/mol
Synonyms	1-Carbobenzoxy-2-n-propylpiperazine hydrochloride; 1-(Benzyloxycarbonyl)-2-propylpiperazine hydrochloride; 2-Propyl-1-piperazinecarboxylic acid benzyl ester hydrochloride; N-Cbz-2-n-Propylpiperazine HCl; 1-Cbz-2-Propylpiperazine HCl; Benzyl 2-propylpiperazine-1-carboxylate hydrochloride; 1-(Phenylmethoxy)carbonyl-2-propylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-n-Cbz-2-n-Propylpiperazine-Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.