Description

1N-Cbz-2-n-Butylpiperazine-Hcl is a high-purity, protected piperazine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce the piperazine moiety into peptide backbones to modify stability, bioavailability, and receptor binding.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in asymmetric catalysis and metal complexation.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and pest management research.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Item	Details
Product Name	1N-Cbz-2-n-Butylpiperazine-Hcl
CAS No.	1179361-47-7
Molecular Formula	C16H25ClN2O2
Molecular Weight	312.84 g/mol
Synonyms	1-Carbobenzoxy-2-n-butylpiperazine hydrochloride; 1-(Benzyloxycarbonyl)-2-n-butylpiperazine hydrochloride; 2-n-Butyl-1-(phenylmethoxy)carbonylpiperazine hydrochloride; N-Cbz-2-n-butylpiperazine HCl; 1-N-Cbz-2-butylpiperazine hydrochloride; Piperazine, 1-[(phenylmethoxy)carbonyl]-2-butyl-, hydrochloride (1:1); (2-Butylpiperazin-1-yl)(phenyl)methanone hydrochloride
EINECS	Contact for details

Quality Control

Our 1N-Cbz-2-n-Butylpiperazine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.