Description

tert-Butyl 4-(4-Bromophenyl)-3-oxopiperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and bromophenyl substituent. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and central nervous system (CNS) active drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting protein kinases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the multi-step synthesis of potential APIs.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	tert-Butyl 4-(4-Bromophenyl)-3-oxopiperazine-1-carboxylate
CAS No.	1178953-47-3
Molecular Formula	C15H19BrN2O3
Molecular Weight	355.23 g/mol
Synonyms	1-Boc-4-(4-bromophenyl)-3-oxopiperazine; 1-(tert-Butoxycarbonyl)-4-(4-bromophenyl)-2,3-dioxopiperazine; tert-Butyl 4-(4-bromophenyl)-2,3-dioxo-1-piperazinecarboxylate; 4-(4-Bromophenyl)-3-oxo-1-piperazinecarboxylic acid tert-butyl ester; 1-N-Boc-4-(4-bromophenyl)piperazine-2,3-dione; BOC-4-(4-Bromophenyl)-3-oxopiperazine; 1178953-47-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Bromophenyl)-3-oxopiperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.