Description

2-(Piperazin-1-Ylmethyl)-1H-Benzimidazole Dihydrochloride is a high-purity, functionalized benzimidazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological intermediate and a versatile building block for constructing complex molecules with targeted biological activity. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of oncology, neurology, and infectious diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting protein kinases and other enzymatic pathways.
• Chemical Biology Research: Used as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Ligand Synthesis: Employed in the development of chelating agents or ligands for catalytic and diagnostic applications.
• Academic & R&D: Serves as a valuable reagent for fundamental organic chemistry research and the creation of specialized chemical libraries.

Basic Information

Product Name	2-(Piperazin-1-Ylmethyl)-1H-Benzimidazole Dihydrochloride
CAS No.	1177362-39-8
Molecular Formula	C12H18Cl2N4
Molecular Weight	289.21 g/mol
Synonyms	1H-Benzimidazole, 2-[(1-piperazinyl)methyl]-, dihydrochloride; 2-(Piperazin-1-ylmethyl)-1H-benzo[d]imidazole dihydrochloride; 2-(Piperazin-1-ylmethyl)-1H-benzimidazole dihydrochloride; 2-(Piperazin-1-ylmethyl)benzimidazole dihydrochloride; 2-Piperazin-1-ylmethyl-1H-benzimidazole dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-Ylmethyl)-1H-Benzimidazole Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.