Description

4-(5-Isopropyl-1,2,4-oxadiazol-3-yl)-2-piperazin-1-ylpyrimidine dihydrochloride is a high-purity, non-nucleoside building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a key synthetic intermediate for creating novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. This compound is essential for medicinal chemists and R&D teams in pharmaceutical and biotechnology companies seeking to develop new small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: A valuable precursor in the research and development of potential kinase inhibitors for oncology applications.
• CNS Drug Discovery: Employed in the synthesis of compounds targeting neurological pathways and receptors.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological mechanisms and pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Item	Details
Product Name	4-(5-Isopropyl-1,2,4-oxadiazol-3-yl)-2-piperazin-1-ylpyrimidine Dihydrochloride
CAS No.	1177093-06-9
Molecular Formula	C15H21Cl2N7O
Molecular Weight	386.28 g/mol
Synonyms	2-Piperazin-1-yl-4-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrimidine dihydrochloride; 4-(5-Isopropyl-[1,2,4]oxadiazol-3-yl)-2-piperazin-1-yl-pyrimidine dihydrochloride; 4-(5-(1-Methylethyl)-1,2,4-oxadiazol-3-yl)-2-(1-piperazinyl)pyrimidine dihydrochloride; UNII-9J8S0C8R2M; 9J8S0C8R2M; 4-(5-Isopropyl-1,2,4-oxadiazol-3-yl)-2-(piperazin-1-yl)pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-(5-Isopropyl-1,2,4-oxadiazol-3-yl)-2-piperazin-1-ylpyrimidine dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.